Galectin Symposium
Date and Time: Friday, August 25, 2023, 18:00-20:00 and Saturday, August 26, 2023, 09:00-12:00
Venue: Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
Registration required, free for local and registered participants of Glyco26.
This satellite meeting of the Glyco26 conference will address the roles of galectins in cellular responses associated with physiological and pathological processes. The field of galectins has advanced extensively since the naming of this family of animal lectins in 1994. Now there are over 16 members that have been identified and studied, with some of them, in particular, galectin-1, -3, -4, -7, -8, -9, -10, and -12 being studied more extensively. As of March 2023, over 10,000 papers can be captured in PubMed search using the keyword “galectin”. Many studies have implicated galectins in the pathogenesis of a variety of diseases. In the meantime, the field is becoming increasingly complicated, with galectins being demonstrated to function both extracellularly and intracellularly, and in the latter, in both glycan-dependent and -independent fashions. This meeting is aimed at bringing together molecular and cellular biologists and glycoscientists to address modes of action of various galectins and discuss challenges and opportunities. We plan to have two keynote lectures, several invited talks, and short oral presentations selected from abstracts submitted for poster presentation.
Organizers:
Fu-Tong Liu (Chair)
Hakon Leffler (co-Chair)
Chun-Hung Lin
Hung-Lin Chen
Tentative Schedule
Day 1 _ August 25, 2023
Social Mixer starts from 17:30
18:00 - 18:10 Opening remarks by Fu-Tong Liu and Hakon Leffler
18:10 - 18:30 Introduction : Sean Stowell - " There and back again: A galectin tale"
*****************************************************************************
18:30 - 19:00
THE EMBO KEYNOTE LECTURE
Ludger Johannes - "Conformational glycoswitch to drive the formation of galectin-3 oligomers"
*****************************************************************************
19:00 - 19:20 Invited Talk : Fredrik Zetterberg - "Discovery and development of small molecule galectin-3 inhibitors"
19:20 - 19:30 Short Talk : Hsien-Ya Lin - "Modifying thiodigalactoside-based inhibitors for selective galectins-1 and -3 inhibition"
19:30 - 19:50 Invited Talk : Laia Querol-Cano - "Galectin-mediated protein interactions regulate dendritic cell function"
19:50 - 20:00 Panel Discussion
Day 2 _ August 26, 2023
09:00 - 09:20 Invited Talk : Ralf Jacob - "Late domain mediated EV-recruitment of galectin-3"
09:20 - 09:40 Invited Talk : Yijuang Chern - "Microglial galectin-3 and neuroinflammation-with a specific focus on neurodegenerative diseases"
09:40 - 10:00 Invited Talk : Betty Wu-Hsieh - "Cell intrinsic galectin-3 negatively regulates innate cell functions”
10:00 - 10:10 Short Talk : Chi-Shan Li - "Cytosolic galectin-4 in host-pathogen interaction"
10:10 - 10:20 Short Talk : Tzu-Hui Hsu - "B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis"
10:20 - 10:40 Coffee break
10:40 - 10:50 Short Talk : Yu-Hao Lin - "Liquid-liquid phase separation in regulating galectin-3’s agglutination from biophysical and evolutionary perspectives"
10:50 - 11:10 Invited Talk : John L Wang - "Intracellular galectins: platforms for assembly of macromolecular complexes"
11:10 - 11:40 Keynote Lecture : Vojo Deretic - "Galectins as coordinators of membrane repair, replacement, and renewal"
11:40 - 12:00 Panel Discussion
** Please refer to "Speakers/Satellite Meetings" for more speakers' information**
